Summary of AACR 2014, 2013 in Nakamura Lab

AACR 2014 Presentation

 

1.    SMYD2-dependent PARP1 methylation promotes Poly(ADP-ribosyl)ation activity in cancer cells

Lianhua Piao, Yusuke Nakamura, Ryuji Hamamoto

 

2.    TARBP1, a member of the SPOUT methyltransferase family, is involved in human carcinogenesis

Makoto Nakakido, Yusuke Nakamura, Ryuji Hamamoto

 

3.    Characterization of LASEP3 as a serological and prognostic biomarker and a therapeutic target for lung cancer

Atsushi Takano, Yusuke Nakamura, Yataro Daigo.

 

4.    Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

Houda Alachkar, Martin Mutonga, Suyoun Chung, Yo Matsuo, Wendy Stock, Yusuke Nakamura

 

5.    Ras and EF-hand domain containing as a novel tissue biomarker and a therapeutic target for lung cancer

Yataro Daigo, Atsushi Takano, Yusuke Nakamura

 

6.    Proteomic analysis of citrullinated targets regulated by the p53-PADI4 pathway

Chizu Tanikawa, Koji Ueda, Hidewaki Nakagawa, Yusuke Nakamura, Koichi Matsuda

 

7.    Molecular-cytogenetic analysis of the maternal embryonic leucine-zipper kinase (MELK) oncogene in cancer

Ashley Hardeman, Tatyana A. Grushko, Maria J. Gomez, Mariann Coyle, Yusuke Nakamura, Olufunmilayo I. Olopade

 

8.    Quantitative t cell receptor (tcr) repertoire analysis by next-generation sequencing (ngs) in non-small cell lung cancer patients treated with therapeutic cancer peptide vaccines

Hua Fang, Rui Yamaguchi, Xiao Liu, Yataro Daigo, Satoru Miyano, Yusuke Nakamura

 

9.    Characterization of T cell repertoire in transplanted patients with graft versus host disease using next generation DNA sequencer

Poh Yin Yew, Rui Yamaguchi, Michael Bishop, Amittha Wickrema, Andrew Artz, Satoru Miyano, Yusuke Nakamura

 

10. Recurrent somatic mutations of nitric oxide synthase NOS3, netrin receptor UNC5C and DNA repair genes in muscle-invasive bladder carcinoma

Kai Lee Yap, Kazuma Kiyotani, Kenji Tamura, Miran Jang, Magdeline Montoya, Cory Ganshert, Tomoaki Fujioka, Gary Steinberg, Peter O'Donnell, Yusuke Nakamura

 

11. GALNT6 stabilizes GRP78 protein by O-type glycosylation

Jae-Hyun Park, Suyoun Chung, Jiaying Lin, Koji Ueda, Toyomasa Katagiri, Yusuke Nakamura

 

12. PSCA as a potential therapeutic and prognostic biomarker for common cancer

Koichi Matsuda, Chizu Tanikawa, Yusuke Nakamura

 

13. Wolf-Hirschhorn syndrome candidate 1 as a potential novel therapeutic target for head and neck cancer

Vassiliki Saloura, Makoto Nakakido, Houda Alachkar, Tanguy Seiwert, Mark Lingen, Ezra Cohen, Yusuke Nakamura, Ryuji Hamamoto.

 

14. The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination in human cancer

Ryuji Hamamoto, Yusuke Nakamura.

 

15. The histone methyltransferase SUV39H2 is a novel target of anticancer therapy

Kembun Sone, Yusuke Nakamura, Ryuji Hamamoto

 

 

AACR 2013 Presentation

 

1.    GWAS, Sequencing, and Immunogenomics in Cancer Research

       Yusuke Nakamura

 

2.    Identification and functional analysis of p53MRA as a novel p53 target gene.

Yuki Funauchi, Chizu Tanikawa, Paulisally Hau Yi Lo, Yusuke Nakamura, Koichi Matsuda.

 

3.    Quantitative cell surface proteome profiling of CD4+ T cells to identify potential therapeutic targets for adult T-cell leukemia (ATL)

Makoto Ishihara, Natsumi Araya, Tomoo Sato, Atae Utsunomiya, Yoshihisa Yamano, Yusuke Nakamura, Hidewaki Nakagawa, Koji Ueda

 

4.    Epstein-Barr Virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer

Yataro Daigo, Atsushi Takano, Yusuke Nakamura

 

5.    A genome-wide association study of HCV induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at MHC region

Matsuda Koichi, Chizu Tanikawa, Yusuke Nakamura

 

6.    Definition of biosimilars: Energy Resolved Oxonium Ion Monitoring (Erexim) technology grasps detailed N-glycan microheterogeneity on therapeutic antibodies

Koji Ueda, Atsuhiko Toyama, Taka-Aki Sato, Yusuke Nakamura, Hidewaki Nakagawa

 

7.    A genome-wide association study identifies PSCA as a susceptibility locus for gastric cancer and duodenal ulcer in the Japanese population

Chizu Tanikawa, Koichi Matsuda, Yusuke Nakamura

 

8.    Wolf-Hirschhorn syndrome candidate 1 plays an important role in the pathogenesis of head and neck cancer

Vassiliki Saloura, Hyun-Soo Cho, Mark Lingen, Terri Li, Can Gong, Seiwert Tanguy, Ezra Cohen, Ryuji Hamamoto, Yusuke Nakamura

 

9.    Characterization of a lung cancer growth factor, LASEP3, as a serological and prognostic biomarker and a therapeutic target

Atsushi Takano, Yusuke Nakamura, Yataro Daigo

 

10. Cancer testis antigens-specific CD4+ T-cell immunity augmented by CTL-epitopes vaccination in cancer patients

Yusuke Tomita, Akira Yuno, Yoshihiro Yoshitake, Hirotake Tsukamoto, Atsushi Irie, Satoru Senju, Koji Yoshida, Takuya Tsunoda, Yusuke Nakamura, Masanori Shinohara, Yasuharu Nishimura

 

11. Functional SNP in MICA binding to SP1 is associated with HCV-induced hepatocellular carcinoma

Paulisally H. Lo, Chizu Tanikawa, Yusuke Nakamura, Koichi Matsuda.

 

12. Development of an orally-administrative MELK (maternal embryonic leucine zipper kinase)-targeting small molecule inhibitor that suppresses the growth of various types of human cancer

Suyoun Chung, Hanae Suzuki, Takashi Miyamoto, Naofumi Takamatsu, Ayako Tatsuguchi, Koji Ueda, Kyoko Kijima, Yo Matsuo, Yusuke Nakamura