Publications

 

 

 

Publication list

Journal

Total

Am. J. Human Genetics

34

Cancer Research

115

Cell

2

Clinical Cancer Research

37

Genomics

84

Human Molecular Genetics

61

Lancet

6

Molecular Cell

1

Nature

17

Nature Cell Biology

2

Nature Communications

5

Nature Genetics

70

Neoplasia

17

New Eng. J. Med.

7

Oncogene

51

OncoImmunology

8

Oncotarget

18

Proc. Natl. Acad. Sci. USA

8

Science

11

Science Translational Medicine

1

Others

912

Total

1466

 

(2017)

  1. Y. Shindo, S. Hazama, Y. Nakamura, Y. Inoue, S. Kanekiyo,  K. Sakamoto, M. Iida, Y. Tokumitsu, H. Matsui, Y. Watanabe, N. Suzuki, H. Takenouchi, R. Tsunedomi, Y. Maeda, N Maeda, M. Nakashima, T. Ueno, S. Takeda, S. Yoshino, K. Okuno, F. Sugiura, Y. Fujita, Y. Hamamoto, M. Okamoto, T. Fujita, Y. Kawakami, M. Oka, aand H. Nagano:  miR-196b, miR-378a and miR-486 are possible predictive biomarkers for the efficacy of the vaccine treatment; from the results of phase I and II studies for metastatic colorectal cancer. Oncology Letter, :DOI: 10.3892/ol.2017.6303, 2017
  2. T.H. Mai, A. Takano, H. Suzuki, T. Hirose, T. Mori, K. Teramoto, K. Kiyotani, Y. Nakamura, and Y. Daigo: Quantitative analysis and clonal characterization of T-cell receptor beta repertoires in advanced non-small cell lung cancer patients treated with cancer vaccine treatment. Oncology Letters, :DOI: 10.3892/ol.2017.6125, 2017
  3. J. Lin, S. Chung, K. Ueda, K. Matsuda, Y. Nakamura, J.-H. Park: GALNT6 stabilizes GRP78 protein by O-glycosylation and enhances its activity to suppress apoptosis under stress condition. Neoplasia, 19:43-53, 2017
  4. P. Haycock, S. Burgess, A. Nounu et al.  The association between genetically 1 elevated telomere length and risk of cancer and non-neoplastic diseases. JAMA Oncology, :doi:10.1001/jamaoncol.2016.5945, 2017
  5. K. Kiyotani, J.-H. Park, H. Inoue, A. Husain, S. Olugbile, M. Zewde, Y. Nakamura, and W.T. Vigneswaran: Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma. Oncoimmunology, :doi.org/10.1080/2162402X.2016.1278330, 2017
  6. V. Saloura, T. Vougiouklakis, M. Zewde, X. Deng, K. Kiyotani, J.-H. Park, Y. Matsuo, M. Lingen, R. Hamamoto, and Y. Nakamura WHSC1L1-mediated EGFR monomethylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR. Scientific Reports, :doi:  10.1038/srep40664, 2017
  7. J.-H. Park, H. Inoue, T. Kato, M. Zewde, T. Miyamoto, Y. Matsuo, R. Salgia, and Y. Nakamura: TOPK (T–lymphokine-activated killer cell–originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer. Cancer Science, :DOI: 10.1111/cas.1316, 2017
  8. W.J. Seow, K. Matsuo, C.A. Hsiung et al.:  Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations. Human Molecular Genetics, 26:454-465, 2017
  9. A. Nagai, M. Hirata, Y. Kamatani, K. Muto, K. Matsuda, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, Z. Yamagata, T. Mushiroda, Y. Murakami, K. Yujil, Y. Furukawa, H. Zembutsu, T Tanaka, Y. Ohnishi, Yusuke Nakamura, BioBank Japan Cooperative Hospital Group, and M. Kubo:  Overview of the BioBank Japan Project: Study design and profile.  Journal of Epidemiology, 27:S2-S8, 2017
  10. M. Hirata, Y. Kamatani, A. Nagai, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, Z. Yamagata, M. Kubo, K. Muto, T. Mushiroda, Y. Murakami, K. Yuji, Y. Furukawa, H. Zembutsu, T. Tanaka, Y. Ohnishio, Y. Nakamura, BioBank Japan Cooperative Hospital Group, and Koichi Matsuda:  Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases. Journal of Epidemiology, 27:S9-S21, 2017
  11. M. Hirata, A. Nagai, Y. Kamatani, T. Ninomiya, A. Tamakoshi, Z. Yamagata, M. Kubo, K. Muto, Y. Kiyohara, T. Mushiroda, Y. Murakami, K. Yuji, Y. Furukawa, H. Zembutsu, T. Tanaka, Y. Ohnishi, Y. Nakamura, BioBank Japan Cooperative Hospital Group, and K. Matsuda:  Overview of BioBank Japan follow-up data in 32 diseases. Journal of Epidemiology, 27:S22-S28, 2017
  12. E. Okada, S. Ukawa, K. Nakamura, M. Hirata, A. Nagai, Y. Kamatani, Z. Yamagata, Y. Kiyohara, T. Ninomiya, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, the BioBank Japan Cooperative Hospital Group, and A. Tamakoshi:  Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project Journal of Epidemiology, 27:S29-S35, 2017
  13. A. Tamakoshi, K. Nakamura, S. Ukawa, E. Okada, M Hirata, A. Nagai, K. Matsuda, Y. Kamatani, K. Muto, Y Kiyohara, Z. Yamagata, T. Ninomiya, M. Kubo, Y. Nakamura, and BioBank Japan Cooperative Hospital Group: Characteristics and prognosis of Japanese colorectal cancer patients: The BioBank Japan Project. Journal of Epidemiology, 27:S36-S42, 2017
  14. S. Ukawa, E. Okada, K. Nakamura, M. Hirata, A. Nagai, Y. Kamatani, Z. Yamagata, Y. Kiyohara, T. Ninomiya, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, the BioBank Japan Cooperative Hospital Group, and A. Tamakoshi:  Characteristics of patients with liver cancer in the BioBank Japan Project. Journal of Epidemiology, 27:S43-S48, 2017
  15. K. Nakamura, S. Ukawa, E. Okada, M Hirata, A. Nagai, Z. Yamagata, T. Ninomiya, K. Muto, Y. Kiyohara, K. Matsuda, Y. Kamatani, M. Kubo, Y. Nakamura, BioBank Japan Cooperative Hospital Group and A. Tamakoshi: Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan project. Journal of Epidemiology, 27:S49-S57, 2017
  16. K. Nakamura, E. Okada, S. Ukawa, M Hirata, A. Nagai, Z. Yamagata, Y. Kiyohara, K. Muto, Y. Kamatani, T. Ninomiya, K. Matsuda, M. Kubo, Y. Nakamura, BioBank Japan Cooperative Hospital Group and A. Tamakoshi: Characteristics and prognosis of Japanese female breast cancer patients: The BioBank Japan project. Journal of Epidemiology, 27:S58-S64, 2017
  17. S. Ukawa, K. Nakamura, E. Okada, M. Hirata, A. Nagai, Y. Kamatani, Z. Yamagata, Y. Kiyohara, T. Ninomiya, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, the BioBank Japan Cooperative Hospital Group, and A. Tamakoshi:  Clinical and histopathological characteristics of patients with prostate cancer in the BioBank Japan Project. Journal of Epidemiology, 27:S65-S70, 2017
  18. J. Hata, A. Nagai, M. Hirata, Y. Kamatani, A. Tamakoshi, Z. Yamagata, K. Muto, K. Matsuda, M. Kubo, Y. Nakamura, Y. Kiyohara, T. Ninomiya, and Biobank Japan Cooperative Hospital Group:  Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project Journal of Epidemiology, 27:S71-S76, 2017
  19. H. Yokomichi, H. Noda, A. Nagai, M. Hirata, Y. Kamatani, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, BioBank Japan Cooperative Hospital Group, and Z. Yamagata:  Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan. Journal of Epidemiology, 27:S77-S83, 2017
  20. H. Yokomichi, H. Noda, A. Nagai, M. Hirata, Y. Kamatani, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, BioBank Japan Cooperative Hospital Group, and Z. Yamagata:  Statin use and all-cause and cancer mortality: BioBank Japan cohort Journal of Epidemiology, 27:S84-S91, 2017
  21. H. Yokomichi, H. Noda, A. Nagai, M. Hirata, Y. Kamatani, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, BioBank Japan Cooperative Hospital Group, and Z. Yamagata:  Serum glucose, cholesterol and blood pressure levels in Japanese patients with type 1 and 2 diabetes: BioBank Japan cohort. Journal of Epidemiology, 27:S92-S97, 2017
  22. H. Yokomichi, H. Noda, A. Nagai, M. Hirata, Y. Kamatani, Y. Kiyohara, T. Ninomiya, A. Tamakoshi, K. Matsuda, K. Muto, M. Kubo, Y. Nakamura, BioBank Japan Cooperative Hospital Group, and Z. Yamagata:  Chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort. Journal of Epidemiology, 27:S98-S106, 2017
  23. Y. Yoshioka, T. Suzuki, Y. Matsuo, G. Tsurita, T. Watanabe, N. Dohmae, Y. Nakamura and R. Hamamoto: Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization. Cancer Medicine, 6:1665-1672, 2017
  24. Y. Ikeda, K. Kiyotani, P.Y. Yew, S. Sato, Y. Imai, R. Yamaguchi, S. Miyano, K. Fujiwara, K. Hasegawa, and Y. Nakamura: Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer. Oncology Reports, :DOI: 10.3892/or.2017.5536, 2017
  25. X. Deng, R. Hamamoto, T. Vougiouklakis, T. Suzuki, N. Dohmae, J.-H. Park and Y. Nakamura: Critical roles of SMYD2-mediated b-catenin methylation for nuclear translocation and activation of Wnt signaling. Oncotarget, in press, 2017
  26. Y. Uno, R. Takata, G. Kito, H. Yamazaki, K. Nakagawa, Y. Nakamura, T. Kamataki, and T. Katagiri: Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes. Drug Metabolism and Pharmacokinetics, 32:100-107, 2017
  27. V. Saloura, A. Fatima, M. Zewde, K. Kiyotani, R. Brisson, J.-H. Park, Y. Ikeda, T. Vougiouklakis, T. Seiwert, N. Cipriani, M. Lingen, E. Vokes, and Y. Nakamura: Characterization of the T-cell receptor repertoire in patients with locoregionally advanced squamous cell carcinoma of the head and neck. Clinical Cancer Research, :DOI: 10.1158/1078-0432.CCR-17-0103, 2017
  28. Y. Shindo, S. Hazama, N. Suzuki, H. Iguchi, K. Uesugi, H. Tanaka, A. Aruga, T. Hatori, H. Ishizaki, Y. Umeda, T. Fujiwara, T. Ikemoto, M. Shimada, K. Yoshimatsu, H. Takenouchi, H. Matsui, S. Kanekiyo, M. Iida, Y. Koki, H. Arima, H. Furukawa, T. Ueno, S. Yoshino, T. Fujita, Y. Kawakami, Y. Nakamura, M. Oka and H. Nagano: Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer. Journal of Experimental & Clinical Cancer Research, :DOI 10.1186/s13046-017-0509-1, 2017
  29. T. Chiyoda, P.C. Hart, M.A. Eckert, S.M. McGregor, R.R. Lastra, R. Hamamoto, Y. Nakamura, S.D. Yamada, O.I. Olopade, E. Lengyel and I.L. Romero: Loss of BRCA1 in the cells of origin of ovarian cancer induces glycolysis: A window of opportunity for ovarian cancer chemoprevention. Cancer Prevention Research, :DOI: 10.1158/1940-6207.CAPR-16-0281 , 2017
  30. W. Obara, F. Sato, K. Takeda, R. Kato, Y. Kato, M. Kanehira, R.  Takata, H. Mimata, T. Sugai, Y. Nakamura, and T. Fujioka: Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer. Cancer Science, :DOI: 10.1111/cas.13278, 2017
  31. R. Wang, X. Deng, Y. Yoshioka, T. Vougiouklakis, J.H. Park, T. Suzuki, N. Dohmae, K. Ueda, R. Hamamoto, and Y. Nakamura: Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small cell lung cancer cells. Cancer Science, :DOI: 10.1111/cas.13245, 2017
  32. T.M. Dudenkov, J.N. Ingle, A.U. Buzdar, M.E. Robson, M. Kubo, I. Ibrahim-Zada, A. Batzler, G.D. Jenkins, T.L. Pietrzak, E.E. Carlson, P. Barman, M.P. Goetz, D.W. Northfelt, A. Moreno-Aspita, C.V. Williard, K.R. Kalari, Y. Nakamura, L. Wang, R.M. Weinshilboum: SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Breast Cancer Research and Treatment, :DOI 10.1007/s10549-017-4243-3, 2017
  33. Y. Fujiwara, K. Okada, T. Omori, K. Sugimura, H. Miyata, M. Ohue, S. Kobayashi, H. Takahashi, H. Nakano, C Mochizuki, K. Shimizu, M. Yano, Y. Nakamura, M. Mori and Y. Doki: Multiple therapeutic peptide vaccines for patients with advanced gastric cancer. International Journal of Oncology, 50:1655-1662, 2017
  34. T. Kato, T. Iwasaki, M. Uemura, A. Nagahara, H. Higashihara, K. Osuga, Y. Ikeda, K. Kiyotani, J.-H. Park, N. Nonomura and Y. Nakamura: Characterization of the cryoablation-induced immune response in kidney cancer. OncoImmunology, :DOI: 10.1080/2162402X.2017.1326441, 2017
  35. T. Matsuda, T. Kato, K. Kiyotani, Y.E. Tarhan, V. Saloura, S. Chung, Y. Nakamura and J.H. Park:  p53-independent p21 induction by MELK inhibition. Oncotarget, :DOI: 10.1080/2162402X.2017.1326441, 2017
  36. C. Tanikawa, Y.-z. Zhang, R. Yamamoto, Y. Tsuda, M. Tanaka, Y. Funauchi, J. Mori, S. Imoto, R. Yamaguchi, Y. Nakamura, S. Miyano, H. Nakagawa, and K. Matsuda: The transcriptional landscape of p53 signalling pathway eBioMedicine, 20:109-119, 2017
  37. T. Kato, J.-H. Park, K. Kiyotani, Y. Ikeda, Y. Miyoshi and Y. Nakamura: Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers. Oncotarget, in press, 2017
  38. S. Sato, T. Nakamura, T. Katagiri, T. Tsuchikawa, T. Kushibiki, K. Hontani, M. Takahashi, K. Inoko, H. Takano, H. Abe, S. Takeuchi, Y. Nakamura, and S. Hirano: Molecular targeting cell permeable peptide inhibits pancreatic ductal adenocarcinoma cell proliferation. Oncotarget, in press, 2017
  39. Y. Fujiwara, K. Sugimura, H. Miyata, T. Omori, H. Nakano, C. Mochizuki, K. Shimizu, H. Saito, K. Ashida, S. Honjyo, Y. Nakamura, and M. Yano: A pilot study of post-operative adjuvant vaccine for advanced gastric cancer. Yonago Acta Medica, 60:101-105, 2017

(2016)

  1. K. Tamura, S. Hazama, R. Yamaguchi, S. Imoto, H. Takenouchi, Y. Inoue, S. Kanekiyo, Y. Shindo, S. Miyano, Y. Nakamura, and K. Kiyotani: Characterization of T cell repertoire in tumor tissues and blood in advanced colorectal cancers through deep T cell receptor sequencing. Oncology Letters, 11:3643-3649, 2016
  2. M. Leisegang, B. Engels, K. Schreiber, P.Y. Yew, K. Kiyotani, C. Idel, A. Arina, J. Duraiswamy, R.R. Weichselbaum, W. Uckert, Y. Nakamura and H. Schreiber:  Eradication of large solid tumors by gene therapy with a T cell receptor targeting a single cancerspecific point mutation. Clinical Cancer Research, :DOI: 10.1158/1078-0432.CCR-15-2361, 2016
  3. H. Alachkar, and Y. Nakamura: Deep Sequencing of the T-cell receptor repertoire in Patients with haplo-cord and matched-donor transplant (review). Chimerism, DOI:10.1080/19381956.2015.1128624, 2016
  4. N. Choudhury, and Y. Nakamura The importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies  Cancer Science, :DOI: 10.1111/cas.12862, 2016
  5. A. Stefka, S. Keys, J.-H. Park, Y. Matsuo, S. Chung, Y. Nakamura, A.J. Jakubowiak, and S. Rosebeck: Inhibition of maternal embryonic leucine zipper kinase (MELK) is cytotoxic to myeloma cells, overcomes drug resistance, and impairs putative myeloma stem cell replenishment of malignant plasma cells.   Blood Cancer Journal, 6:doi:10.1038/bcj.2016.71, 2016
  6. D. Hertz, , K. Owzar, S. Lessans, C. Wing, C. Jiang, W. Kelly, J. Patel, S. Halabi, Y. Furukawa, H. Wheeler, A. Sibley, C. Lassiter, L. Weisman, D. Watson, S. Krens, F. Mulkey, C. Renn, E. Small, P. Febbo, I. Shterev, D. Kroetz, P. Friedman, J. Mahoney, M. Carducci, M. Kelley, Y. Nakamura, M. Kubo, S. Dorsey, M.E Dolan, M. Morris, M. Ratain, and H. McLeod: Pharmacogenetic discovery in CALGB (Alliance) 90401 and mechanistic validation of a VAC14 polymorphism that increases risk of docetaxel-induced neuropathy. Clinical Cancer Research, :doi: 10.1158/1078-0432.CCR-15-2823 , 2016
  7. Y. Ikeda, K. Kiyotani, P.Y. Yew, T. Kato, K. Tamura, K.-L. Yap, S.M. Nielsen, J.L. Mester, C. Eng, Y. Nakamura, and R.H. Grogan: Germline PARP4 mutations in patients with primary thyroid and breast cancers. Endocrine-Related Cancer, :doi: 10.1530/ERC-15-0359, 2016
  8. J. Mori, C. Tanikawa, Y. Funauchi, P.H.Y. Lo, Y. Nakamura and K. Matsuda Cystatin C as a p53-inducible apoptotic mediator which regulates Cathepsin L activity. Cancer Science, :DOI: 10.1111/cas.12881, 2016
  9. R. Hamamoto, and Yusuke Nakamura: Dysregulation of protein methyltransferases in human cancer: an emerging target class for anticancer therapy. Cancer Science, :DOI: 10.1111/cas.12884, 2016
  10. C.G. Chapman, R. Yamaguchi, K. Tamura, J. Weidner, S. Imoto, J Kwon, H Fang, P.-Y. Yew, S.R. Marino, S. Miyano, Y. Nakamura, and K. Kiyotani: Characterization of T-cell receptor repertoire in inflamed tissues of patients with Crohn’s disease through deep sequencing. Immflamatory Bowel Diseases, :doi: 10.1097/MIB.0000000000000752, 2016
  11. M. Gupta, D. Neavin, D. Liu, J. Biernacka, D. Hall-Flavin, W. Bobo, M. Frye, M. Skime, G. Jenkins, A. Batzler, K. Kalari, W. Matson, S. Bhasin, H. Zhu, T. Mushiroda, Y. Nakamura, M. Kubo, L. Wang, R. Kaddurah-Daouk, and R. Weinshilboum: TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: Pharmacometabolomics-informed pharmacogenomics. Molecular Psychiatry, :doi:10.1038/mp.2016.6, 2016
  12. L. Piao, M. Nakakido, T. Suzuki, N. Dohmae, Y. Nakamura and R. Hamamoto:  Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins. Oncotarget, :doi: 10.18632/oncotarget.8072, 2016
  13. T. Kato, H. Inoue, S. Imoto, Y. Tamada, T. Miyamoto, Y. Matsuo, Y. Nakamura and J.-H. Park: Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells. Oncotarget, :DOI: 10.18632/oncotarget.7755, 2016
  14. H. Inoue, T. Kato, S. Olugbile, K. Tamura, S. Chung, T. Miyamoto, Y. Matsuo, R. Salgia, Y. Nakamura, and J.-H. Park: Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.  Oncotarget, :DOI: 10.18632/oncotarget.7297, 2016
  15. H. Alachkar, N. Fulton, B. Sanford, G. Malnassy, M. Mutonga, R. Larson, C. Bloomfield, G. Marcucci, Y. Nakamura, and W. Stock: Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and Asparaginase induced hepatotoxicity in adult patients with Acute Lymphoblastic Leukemia. The Pharmacogenomics Journal, :doi:10.1038/tpj.2016.7, 2016
  16. Chung, K. Kijima, A. Kudo, Y. Fujisawa, Y. Harada, A. Taira, N. Takamatsu, T. Miyamoto, Y. Matsuo, and Y. Nakamura: Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor. Oncotarget, :DOI: 10.18632/oncotarget.7685, 2016
  17. N.J. Choudhury, A. Campanile, T. Antic, K.L. Yap, C. Fitzpatrick, J.L. Wade III, T. Karrison, W.M. Stadler, Y. Nakamura, P.H. O’Donnell:  Afatinib activity in platinum-refractory metastatic urothelial carcinoma in patients with ERBB alterations. Journal of Clinical Oncology, :doi: 10.1111/cas.12862, 2016
  18. J.-H. Park, M. Jang, Y.E. Tarhan, T. Katagiri, M. Sasa, Y. Miyoshi, K.R. Kalari, V.J. Suman, R. Weinshilboum, L. Wang,  J.C. Boughey,  M.P. Goetz, and Y. Nakamura: Clonal expansion of anti-tumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy.  International Journal of Oncology, :DOI: 10.3892/ijo.2016.3540, 2016
  19. M. Murahashi, Y. Hijikata, K. Yamada, Y. Tanaka, J. Kishimoto, S. Okano, H. Inoue, T. Marumoto, A. Takahashi, T. Okazaki, K. Takeda, M. Hirakawa, M. Morita, E. Baba, K. Mizumoto, Y. Maehara, M. Tanaka, K. Akashi, Y. Nakanishi, K. Yoshida, T. Tsunoda, K. Tamura, Y. Nakamura, and K. Tani: Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors. Clinical Immunology, :doi.org/10.1016/j.clim.2016.03.015, 2016
  20. Y.E. Tarhan, T. Kato, M. Jang, Y. Haga, K. Ueda, Y. Nakamura, and J.-H. Park: Morphological changes, cadherin switching and growth suppression in pancreatic cancer by GALNT6 knockdown. Neoplasia, 18:265–272, 2016
  21. F.N.G. van ’t Hof , Y.M. Ruigrok, S. Ripke, G. Anderson, M. de Andrade, A.F. Baas, Jan D. Blankensteijn, E.P. Böttinger, M.J. Bown, J. Broderick, P. Bijlenga, D.S. Carrell, D.C. Crawford, D.R. Crosslin, C. Ebeling, J.G. Eriksson, M. Fornage, T. Foroud, M. von und zu Fraunberg, C.M. Friedrich, E.I. Gaál, O. Gottesman, D.-c. Guo, S.C. Harrison, J. Hernesniemi, A. Hofman, I. Inoue, J.E. Jääskeläinen, G.T. Jones, L.A.L.M. Kiemeney, R. Kivisaari, N. Ko, S. Koskinen, M. Kubo, I.J. Kullo, H. Kuivaniemi, M.I. Kurki, A. Laakso, D. Lai, S.M. Leal, H. Lehto, S.A. LeMaire, S.-K. Low, J. Malinowski, C.A. McCarty, D.M. Milewicz, T.H. Mosley, Y. Nakamura, H. Nakaoka, M. Niemelä, J. Pacheco, P.L. Peissig, J. Pera, L. Rasmussen-Torvik, M.D. Ritchie, F. Rivadeneira, A.M. van Rij, R.L.P. Santos-Cortez, A. Saratzis, A. Slowik, A. Takahashi, G. Tromp, A.G. Uitterlinden, S.S. Verma, S.H. Vermeulen, G.T. Wang, Aneurysm Consortium Vascular Research Consortium of New Zealand, G.J.E. Rinkel, P.I.W. de Bakker: Shared genetic risk factors of intracranial, abdominal and thoracic aneurysms. JAHA, :doi: 10.1161/JAHA.115.002603, 2016
  22. V. Saloura, T. Vougiouklakis, M. Zewde, K. Kiyotani, J.-H. Park, G. Gao, T. Karrison, M. Lingen, Y. Nakamura, and R. Hamamoto:  WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck. Oncotarget, :DOI: 10.18632/oncotarget.989, 2016
  23. T. Kimura, S. Fukushima, A. Miyashita, J. Aoi, M. Jinnin, T. Kosaka, M. Matsukawa, H. Inoue, K. Kiyotani, J.-H. Park, Y. Nakamura, and H. Ihn: Myasthenic crisis and polymyositis induced by one dose of nivolumab.  Cancer Science, 107:1055–1058 (doi: 10.1111/cas.12961), 2016
  24. Y. Ikeda, J.-H. Park, T. Miyamoto, N. Takamatsu, T. Kato, A. Iwasa, S. Okabe, Y. Imai, K. Fujiwara, Y. Nakamura and K. Hasegawa:  T-LAK cell-originated protein kinase (TOPK) as a prognostic factor and a potential therapeutic target in ovarian cancer. Clinical Cancer Research, doi:10.1158/1078-0432.CCR-16-0207, 2016
  25. Y.-M. Chin, L.P. Tan, N.A. Aziz, T. Mushiroda , M. Kubo, N.K.M. Kornain, G.W. Tan, A.S.-B. Khoo, G. Krishnan, K.-C. Pua, Y.-Y. Yap, S.-H. Teo , P.V.-H. Lim, Y. Nakamura, C.L. Lum , The Malaysian NPC Study Group, and C,-C, Ng: Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort. International Journal of Cancer, DOI: 10.1002/ijc.30207, 2016
  26. M. Nakakido, K. Tamura, S. Chung, K. Ueda, R. Fujii, K. Kiyotani, and Y. Nakamura:  Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors. International Journal of Oncology, :doi:  10.3892/ijo.2016.3607, 2016
  27. H. Inoue, J.-H. Park, K. Kiyotani, M. Zewde, A. Miyashita, J. Masatoshi, Y. Kiniwa, R. Okuyama, R. Tanaka, Y. Fujisawa, H. Kato, A. Morita, J. Asai, N. Katoh, K. Yokota, M. Akiyama, H. Ihn, S. Fukushima and Y. Nakamura: Intratumoral expression levels of PD-L1, GZMA, and HLA-A associated with oligoclonal T cell expansion predict response to nivolumab in metastatic melanoma. OncoImmunology, doi.org/10.1080/2162402X.2016.1204507, 2016
  28. T. Nakamura, T. Katagiri, S. Sato, T. Kushibiki, K. Taniuchi, M. Iiizumi, T. Tsuchikawa, S. Hirano and Y. Nakamura: Overexpression of C16orf74 is involved in aggressive pancreatic cancers. Oncotarget, :DOI: 10.18632/oncotarget.10912, 2016
  29. K. Shiraishi, Y. Okada, A. Takahashi, Y. Kamatani, Y. Momozawa, K. Ashikawa, H. Kunitoh, S. Matsumoto, A. Takano, K. Shimizu, A. Goto, K. Tsuta, S. Watanabe, Y. Ohe, Y. Watanabe, Y. Goto, H. Nokihara, K. Furuta, A. Yoshida, K. Goto, T. Hishida, M. Tsuboi, K. Tsuchihara, Y. Miyagi, H. Nakayama, T. Yokose, K. Tanaka, T. Nagashima, Y. Ohtaki, D. Maeda, K. Imai, Y. Minamiya, H. Sakamoto, A. Saito, Y. Shimada, K. Sunami, M. Saito, J. Inazawa, Y. Nakamura, T. Yoshida, J. Yokota, F. Matsuda, K. Matsuo, Y. Daigo, M. Kubo, and T. Kohno: Association of variations in HLA-class II and other loci with susceptibility to EGFR3 mutated lung adenocarcinoma. Nature Communications, :doi:10.1038/ncomms12451, 2016
  30. Y. Yoshioka, T. Suzuki, Y. Matsuo, M. Nakakido, G. Tsurita, C. Simone, T. Watanabe, N. Dohmae, Y. Nakamura and R. Hamamoto:  SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1. Oncotarget, :DOI: 10.18632/oncotarget.11898, 2016
  31. W. Obara, T. Karashima, K. Takeda, T. Katagiri, R. Kato, Y. Kato, M. Kanehira, R. Takata, K. Inoue, T. Shuin, Y. Nakamura, and T. Fujioka: Effective induction of cytotoxic T cells recognizing an epitope peptide derived from Hypoxia-Inducible Protein 2 (HIG2) in patients with metastatic renal cell carcinoma.  Cancer Immunology Immunotherapy, :DOI 10.1007/s00262-016-1915-5, 2016
  32. J.-H. Park, S. Chung, Y. Matsuo, and Y. Nakamura:  Development of small molecular compounds targeting cancer stem cells. (Review) MedChemComm, :DOI: 10.1039/c6md00385k, 2016
  33. K.L. Yap, L.V. Furtado, K. Kiyotani, E. Curran, W. Stock, J.L. McNeer, S.Kadri, J. Segal, Y. Nakamura, M.M. Le Beau, S. Gurbuxani, G. Raca: Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL). Leukemia & Lymphoma, :DOI: 10.1080/10428194.2016.1219902, 2016
  34. H. Zembutsu, S. Nakamura, S. Akashi-Tanaka, T. Kuwayama, C. Watanabe, T. Takamaru, H. Takei, T. Ishikawa, K Miyahara, H. Matsumoto, Y. Hasegawa, G.Kutomi, H. Shima, F. Satomi, M. Okazaki, H. Zaha, M. Onomura, A. Matsukata, Y. Sagara, S. Baba, A. Yamada, K. Shimada, D. Shimizu, K. Tsugawa, A. Shimo, T.E. Yu, M. Hartman, C.C. Wan, S.C. Lee, and Y. Nakamura: Significant effect of polymorphisms in CYP2D6 on response to tamoxifen therapy for breast cancer; a prospective multicenter study. Clinical Cancer Research, :doi: 10.1158/1078-0432.CCR-16-1779, 2016
  35. K. Kiyotani, T.H. Mai and Y. Nakamura: Comparison of exome-based HLA class I genotyping tools:identification of platform-specific genotyping errors. Journal of Human Genetics, :doi:10.1038/jhg.2016.141, 2016
  36. X. Deng, and Y.Nakamura Cancer precision medicine: from cancer screening to drug selection and personalized immunotherapy. Trends in Pharmacological Sciences, doi.org/10.1016/j.tips.2016.10.013, 2016
  37. N. Suzuki, S. Hazama, H. Iguchi, K. Uesugi, H. Tanaka, K. Hirakawa, A. Aruga, A. Hatori, H. Ishizaki, Y. Umeda, M. Shimada, K. Yoshimatsu, R. Shimizu, H. Hayashi, K. Sakata, H. Takenouchi, H. Matsui, Y. Shindo, M. Iida, H. Koki, H. Arima, H. Furukawa, T. Ueno, S. Yoshino, Y. Nakamura, M. Oka, and H. Nagano: A phase ΙI study of peptides cocktail therapy in combination with gemcitabine as a first-line therapy for advanced pancreatic cancer (VENUS-PC study) Cancer Science, :DOI: 10.1111/cas.13113, 2016
  38. H. Alachkar, M. Mutonga, T. Kato, S. Kalluri; Y. Kakuta, M, Uemura, R, Imamura, N. Nonomura, V. Vujjini, S. Alasfar, H. Rabb, Y. Nakamura, and N. Alachkar: Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection. BMC Nephrology, 17DOI: 10.1186/s12882-016-0395-3, 2016

(2015)

  1. M.P. Goetz, J.X. Sun, V.J. Suman, G.O. Silva, C.M. Perou, Y. Nakamura, N.J. Cox, P.J. Stephens, V.A. Miller, J.S. Ross, D. Chen, S.L. Safgren, M. Kuffel, M.M. Ames, K.R. Kalari, H. Gomez,  A.M. Gonazalez-Angulo, O. Burgues, H. Brauch, J.N. Ingle, M.J. Ratain, and R. Yelensky: Loss of heterozygosity at the CYP2D6 locus in breast cancer:  Implications for germline pharmacogenetic studies. Journal of National Cancer Insititute, 107:dju401, 2015
  2. P.H.Y. Lo, C. Tanikawa, T. Katagiri, Y. Nakamura, and K. Matsuda: Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma Oncology Reports, 33:267-273, 2015
  3. R. Hamamoto, V. Saloura and Y. Nakamura: Critical roles of non-histone protein lysine methylation in human tumorigenesis. (review article) Nature Reviews Cancer, 15:110-124, 2015
  4. X. Liu, G. Venkataraman, J. Lin, K. Kiyotani, S. Smith, M. Montoya, Y. Nakamura, and J. Kline: Highly clonal T cell receptor repertoire among regulatory T cells in follicular lymphoma tissues – correlation with the CD8+ T cell receptor repertoire  OncoImmunology, DOI:10.1080/2162402X. 2014.1002728, 2015
  5. N. Thavichachart, T. Mushiroda, T. Thavichachart, O. Charoensook, A. Prasansuklab, P. Rutchatajumroon, S. Tangwongchai, P. Worakul, B. Kanchanatawan, S. Suppapitiporn, A. Sughondhabirom, C. Roomruangwong, W. Chantratita, A. Takahashi, M. Kubo, N. Kamatani, and Y. Nakamura: Genome-wide association study in Thai Tsunami survivors identified risk alleles for posttraumatic stress disorder. Open Journal of Genetics, 5:43-57, 2015
  6. L. Fares-Taie, S. Gerber, A. Tawara, A. Ramirez-Miranda, J.-Y. Douet, H. Verdin, A. Guilloux, J.C. Zenteno, H. Kondo, H. Moisset, B. Passet, K. Yamamoto, M. Iwai, T. Tanaka, Y. Nakamura, W. Kimura, C. Bole-Feysot, M. Vilotte, S. Odent, J.-L. Vilotte, A. Munnich, A. Regnier, N. Chassaing, E. De Baere, I. Raymond-Letron, J. Kaplan, P. Calvas, O. Roche, J.-M. Rozet:  Submicroscopic deletions at 13q32.1 cause congenital microcoria.  Am. J. Human Genetics, 96:631–639, 2015
  7. C.M. Vachon, D.J. Schaid, J.N. Ingle, D.L. Wickerham, M. Kubo, T. Mushiroda, M.P. Goetz, E.E. Carlson, S. Paik, N. Wolmark, Y. Nakamura, L, Wang, R. Weinshilboum, F.J. Couch: A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.  Breast Cancer Research and Treatment, :DOI 10.1007/s10549-014-3175-4, 2015
  8. K. Kusakabe, N. Ide, Y. Daigo, T. Itoh, T. Yamamoto, H. Hashizume, K. Nozu, H. Yoshida, G. Tadano, S. Tagashira, K. Higashino, Y. Okano, Y. Sato, M. Inoue, M. Iguchi, T. Kanazawa, Y. Ishioka, K. Dohi, Y. Kido, S. Sakamoto, S. Ando, M. Maeda, M. Higaki, Y. Baba, and Y. Nakamura:  Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. Journal of Medicinal Chemistry, :DOI: 10.1021/jm501599u, 2015
  9. Y. Yoshitake, Y. Nishimura, Y. Nakamura, and M. Shinohara: A clinical trial of multiple peptides vaccination for advanced head and neck cancer patients induced immune responses and prolonged OS (review). OncoImmunology, :DOI:10.1080/2162402X.2015.1022307, 2015
  10. M. Nakakido, Z. Deng, T. Suzuki, N. Dohmae, Y. Nakamura and R. Hamamoto: Dysregulation of AKT pathway by SMYD2-mediated lysine methylation on PTEN. Neoplasia, 17:367–373, 2015
  11. M. Jang, P.-Y. Yew, K. Hasegawa, Y. Ikeda, K. Fujiwara, G.F. Fleming, Y. Nakamura, and J.-H. Park: Characterization of T cell repertoire of blood, tumor and ascites in ovarian cancer patients using next generation sequencing. OncoImmunology, :DOI:10.1080/2162402X.2015.1030561, 2015
  12. T. Vougiouklakis, R. Hamamoto, Y. Nakamura, and V. Saloura:  The NSD family of protein methyltransferases in human cancer. (review) Epigenomics, :doi:10.2217/epi.15.32, 2015
  13. K. Kusakabe, N. Ide, Y. Daigo, T. Itoh, T. Yamamoto, E. Kojima, Y. Mitsuoka, G. Tadano, S. Tagashira, K. Higashino, Y. Okano, Y. Sato, M. Inoue, M. Iguchi, T. Kanazawa, Y. Ishioka, K. Dohi, Y. Kido, S. Sakamoto, S. Ando, M. Maeda, M. Higaki, H. Yoshizawa, H. Murai, and Y. Nakamura: A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity. Bioorganic & Medicinal Chemistry , 23:2247–2260, 2015
  14. P.Y. Yew, H. Alachkar, R. Yamaguchi, K. Kiyotani, H. Fang, K.L. Yap, H.T. Liu, A. Wickrema, A. Artz, K. van Besien, S. Imoto, S. Miyano, M.R. Bishop, W. Stock, and Y. Nakamura: Quantitative characterization of T cell repertoire in allogeneic hematopoietic stem cell transplant recipients.  Bone Marrow Transplantation, :doi:10.1038/bmt.2015.133, 2015
  15. M. Komatsu, H.E. Wheeler, S. Chung, S.-K. Low, C. Wing, S.M. Delaney, L.K. Gorsic, A. Takahashi, M. Kubo, D.L. Kroetz, W. Zhang, Y. Nakamura, and M.E. Dolan:  Pharmacoethnicity in paclitaxel-Induced sensory peripheral neuropathy. Clinical Cancer Research, :DOI: 10.1158/1078-0432.CCR-15-0133, 2015
  16. X. Deng, G. VonKeudell, T. Suzuki, N. Dohmae, M. Nakakido, L. Piao, Y. Yoshioka, Y Nakamura and R. Hamamoto: PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP. Oncotarget, :DOI: 10.18632/oncotarget.6050, 2015
  17. L. Piao, T. Suzuki, N. Dohmae, Y. Nakamura and Ryuji Hamamoto: SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells. Oncotarget, :doi:  10.18632/oncotarget.4760, 2015
  18. M. Mutonga, K. Tamura, G. Malnassy, N. Fulton, A. de Albuquerque, R. Hamamoto, W. Stock, Y. Nakamura and H. Alachkar: Targeting Suppressor of Variegation 3-9 Homologue 2 (SUV39H2) in acute lymphoblastic leukemia (ALL). Translational Oncology, :doi:10.1016/j.tranon.2015.07.003, 2015
  19. M. Nakakido, Z. Deng, T. Suzuki, N. Dohmae, Y. Nakamura, and R. Hamamoto:  PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents. Oncotarget, :DOI: 10.18632/oncotarget.5143, 2015
  20. H. Alachkar, M. Mutonga, G. Malnassy, J.-H. Park, N. Fulton, A. Woods, L. Meng, J. Kline, G. Raca, O. Odenike, N. Takamatsu, T. Miyamoto, Y. Matsuo, W. Stock, and Y. Nakamura: T-LAK Cell-Originated Protein Kinase presents a novel therapeutic target in FLT3-ITD mutated Acute Myeloid Leukemia. Oncotarget, :DOI: 10.18632/oncotarget.5418 , 2015
  21. K. Tanakaya, Y. Furukawa, Y. Nakamura, K. Hirata, N. Tomita, K. Tamura, K. Sugano, C. Ishioka, T. Yoshida, H. Ishida, T. Watanabe, and K. Sugihara for HNPCC registry and genetic testing project of the Japanese Society for Cancer of the Colon and Rectum: Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum. Japanese Journal of Clinical Oncology, :doi:10.1093/jjco/hyu218, 2015
  22. Y. Funauchi, C. Tanikawa, P.H.Y. Lo, J. Mori, Y. Daigo, A. Takano, Y. Miyagi, A. Okawa, Y. Nakamura, and K. Matsuda: Regulation of iron homeostasis by p53-ISCU pathway. Scientific Reports, :doi:  10.1038/srep16497, 2015
  23. N.J. Choudhury, K. Kiyotani, K.L. Yap, A. Campanile, T. Antic, P.Y. Yew, G. Steinberg, J.-H. Park, Y. Nakamura, P.H. O’Donnell: Low T cell receptor diversity, high somatic mutation burden, and high neoantigen load as predictors of clinical outcome in muscle-invasive bladder cancer. European Urology Focus, :doi.org/10.1016/j.euf.2015.09.007, 2015
  24. T. Vougiouklakis, K. Sone, V. Saloura, H.-S. Cho, T. Suzuki, N. Dohmae, H. Alachkar, Y. Nakamura and R. Hamamoto: SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells. Oncotarget, :DOI: 10.18632/oncotarget.6351, 2015

(2014)

  1. A. Chhibber, J. Mefford, E. Stahl, S. Pendergrass, R. Baldwin, K. Owzar, M. Li, E. Winer, C. Hudis, H. Zembutsu, M. Kubo, Y. Nakamura, H. McLeod, M. Ratain, L. Shulman, M. Ritchie, R. Plenge, J. Witte and D. Kroetz:  Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).  The Pharmacogenomics Journal, 14:336–342, 2014
  2. Y. Tomita, A. Yuno, H. Tsukamoto, S. Senju, S. Yoshimura, R. Osawa, Y. Kuroda, M. Hirayama, A. Irie, A. Hamada, H. Jono, K.Yoshida, T. Tsunoda, H. Kohrogi, Y. Yoshitake, Y. Nakamura, M. Shinohara, and Y. Nishimura:  Identification of CDCA1 long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients. International Journal of Cancer, 134:352–366, 2014
  3. S. Yoshimura, T. Tsunoda, R. Osawa, M. Harada, T. Watanabe, T. Hikichi, M. Katsuda, M. Miyazawa, M. Tani, M. Iwahashi, K. Takeda, T. Katagiri, Y. Nakamura, and H. Yamaue: Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2). PLoS ONE, 9:e85267, 2014
  4. K. Yamaguchi, R. Yamaguchi, N. Takahashi, T. Ikenoue, T. Fujii, M. Shinozaki, G. Tsurita, K. Hata, A. Niida, S. Imoto, S. Miyano, Y. Nakamura, and Y. Furukawa: Overexpression of Cohesion Establishment Factor DSCC1 through E2F in Colorectal Cancer. PLoS ONE, 9:e85750, 2014
  5. B. Zhang, W.-H. Jia, K. Matsuo, A. Shin, Y.-B. Xiang, K. Matsuda, S. H. Jee, D.-H. Kim, P. Y. Cheah, Z. Ren, Q. Cai, J. Long, J. Shi, W. Wen, G. Yang, B.-T. Ji, Z.-Z. Pan, F. Matsuda, Y.-T. Gao, J. H. Oh, Y.-O. Ahn, M. Kubo, L. F. Thean, E. J. Park, H.-L. Li, J. W. Park, J. Jo, J.-Y. Jeong, S. Hosono, Y. Nakamura, X.-O. Shu, Y.-X. Zeng, and W. Zheng: Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians. International Journal of Cancer, 134:DOI: 10.1002/ijc.28733, 2014
  6. J. Lin, Z. Deng, C. Tanikawa, T. Shuin, T. Miki, K. Matsuda, and Y. Nakamura: Downregulation of a tumor suppresser HSPB7, involved in the p53-pathway, in renal cell carcinoma by hypermethylation. International Journal of Oncology, 5:1490-1498, 2014
  7. Y. Tomita, A. Yuno, H. Tsukamoto, S. Senju, Y. Kuroda, M. Hirayama, Y. Imamura, J. Yatsuda, M.A. Sayem, A. Irie, A. Hamada, H. Jono, K. Yoshida, T. Tsunoda, Y. Daigo, H. Kohrogi, Y. Yoshitake, Y. Nakamura, M. Shinohara, and Y. Nishimura: LY6K-specific CD4+ T-cell immunity in patients with malignant tumor: Identification of LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes. OncoImmunology, 3:DOI: 10.4161/onci.28100, 2014
  8. J.-H. Park, and Y. Nakamura: GALNT6 (UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)) Atlas of Genetic  and Cytpgenetics in Oncology and Hematology, 18:90-92, 2014
  9. Y. Ji, D.J. Schaid, Z. Desta, M. Kubo, A.J. Batzler, K. Snyder, T. Mushiroda, N. Kamatani, E. Ogburn, D. Hall-Flavin, D. Flockhart, Y. Nakamura, D.A. Mrazek, R.M. Weinshilboum: Citalopram and Escitalopram Plasma Drug and Metabolite Concentrations: Genome-Wide Associations. British Journal of Clinical Pharmacology, :DOI: 10.1111/bcp.12348, 2014
  10. L. Piao, D. Kang, T. Suzuki, A. Masuda, N. Dohmae, Y. Nakamura, and R. Hamamoto: The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells. Neoplasia, 16:257-264, 2014
  11. S. Hazama, Y. Nakamura, S. Yoshida, Y. Tokuhisa, S. Tomochika, Y. Inoue, N. Suzuki, S. Yoshino, H. Takenouchi, R. Tsunedomi, N. Iizuka, K. Takeda, and M. Oka: A phase Ι study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome. Journal of Translational Medicine, 12:63, 2014
  12. H. Iinuma, R. Fukushima, T. Inaba, J. Tamura, T. Inoue, M. Horikawa, E. Ogawa, Y. Ikeda, N. Matsutani, K. Takeda, K. Yoshida, T. Tsunoda, T. Ikeda, Y. Nakamura and K. Okinaga: Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients. Journal of Translational Medicine, 12:84, 2014
  13. T. Fujitomo, Y. Daigo, K. Matsuda, K. Ueda and Y. Nakamura: Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis. International Journal of Oncology, 45:147-156, 2014
  14. D. Shigemizu, T. Abe, T. Morizono, T. A. Johnson, K. A. Boroevich, Y. Hirakawa, T. Ninomiya, Y. Kiyohara, M. Kubo, Y. Nakamura, S. Maeda, and T. Tsunoda: The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort. PLoS ONE, :DOI: 10.1371/journal.pone.0092549, 2014
  15. A. Yamada, K. Maeda, K. Kiyotani, T. Mushiroda, Y. Nakamura and Y. Sugiyama: Kinetic interaction of the importance of OATP1B3 and MRP2 in docetaxel induced hematopoietic toxicity. Clinical Pharmacology & Therapeutics, 3:e126, 2014
  16. H. Aguilar, A. Urruticoechea, P. Halonen, K. Kiyotani, T. Mushiroda, X. Barril, J. Serra-Musach, A. Isalam, L. Caizzi, L.D. Croce, E. Nevedomskaya, W. Zwart, J. Bostner, E. Karlsson, G.P. Tenorio, T. Fornander, D.C. Sgroi, R. Garcia-Mata, M.P.H.M. Jansen, N. Garcia, N. Bonifaci, F. Climent, M.T. Soler, A. Rodriguez-Vida, M. Gil, J. Brunet, G. Martrat, L. Gomez-Baldo, A.I. Extremera, A. Figueras, J. Balart, R. Clarke, K.L. Burnstein, K.E. Carlson, J.A. Katzenellenbogen, M. Vizoso, M. Esteller, A. Villanueva, A.B. Rodriguez-Peña, X.R. Bustelo, Y. Nakamura, H. Zembutsu, O. Stal, R.L. Beijersbergen and M.A. Pujana: VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Research, 16:doi:10.1186/bcr3664, 2014
  17. M. Hirokawa, H. Morita, T. Tajima, A. Takahashi, K. Ashikawa, F. Miya, D. Shigemizu, K. Ozaki, Y. Sakata, D. Nakatani, S. Suna, Y. Imai, T. Tanaka, T. Tsunoda, K. Matsuda, T. Kadowaki, Y. Nakamura, R. Nagai, I. Komuro, and M. Kubo: A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese. European Journal of Human Genetics, :doi:10.1038/ejhg.2014.110, 2014
  18. R. Hamamoto, G. Toyokawa, M. Nakakido, K. Ueda, and Y. Nakamura: SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation. Cancer Letters, 351:126–133, 2014
  19. Y. Yamamoto, M. Miyamoto1, D. Tatsuda, M. Kubo, H. Nakagama, Y. Nakamura, H. Satoh, K. Matsuda, T. Watanabe and T. Ohta: A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability. Cancer Research, :DOI: 10.1158/0008-5472, 2014
  20. H. Fang, X. Liu, J. Ramírez, N. Choudhury, H.K. Im, A. Konkashbaev, N.J. Cox, M.J. Ratain, Y. Nakamura, P.H. O’Donnell: Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.  The Pharmacogenomics Journal, :doi:10.1038/tpj.2014.27, 2014
  21. Y.-M. Chin, T. Mushiroda, A. Takahashi, M. Kubo, G. Krishnan , L.-F. Yap, S.-H. Teo, P. V.-H. Lim, Y.-Y. Yap, K.-C. Pua, N. Kamatani ,Y. Nakamura, C.-K. Sam, A. S.-B. Khoo, The Malaysian NPC Study Group and C.-C. Ng: HLA-A SNPs and amino acid variants are associated with nasopharyngeal 1 carcinoma in Malaysian Chinese. International Journal of Cancer, :DOI: 10.1002/ijc.29035, 2014
  22. S. Hazama, Y. Nakamura, H. Tanaka, K. Hirakawa, K. Tahara, R. Shimizu, H. Ozasa, R. Etoh, F. Sugiura, K. Okuno, T. Furuya, T. Nishimura, K. Sakata, K. Yoshimatsu, H. Takenouchi, R. Tsunedomi, Y. Inoue, S. Kanekiyo, Y. Shindo, N. Suzuki, S. Yoshino, H. Shinozaki, A. Kamiya, H. Furukawa, T. Yamanaka, T. Fujita, Y. Kawakami and M. Oka: A phase ΙI study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study). Journal of Translational Medicine, 12:108, 2014
  23. S. Hazama, H. Takenouchi, R. Tsunedomi, M. Iida, N. Iizuka, Y. Inoue, K. Sakamoto, M. Nakao, Y. Shindo, S. Kanekiyo, Y. Tokumitsu, K. Yoshimura, N. Maeda, K. Maeda, Y. Maeda, H. Matsui, S. Yoshino, Y. Nakamura, Y. Fujita, Y. Hamamoto, M. Okamoto, T. Fujita, Y. Kawakami, and M. Oka: Predictive biomarkers for the outcome of vaccination of five therapeutic epitope peptides for colorectal cancer. Anticancer Research, 34:4201-4206, 2014
  24. M.F. Keller, A.P. Reiner, Y. Okada, F.J.A. van Rooij, A.D. Johnson, M.-H. Chen, A.V. Smith, A.P. Morris, T. Tanaka, L. Ferrucci, A.B. Zonderman, G. Lettre, T. Harris, M. Garcia, S. Bandinelli, R. Qayyum, L.R. Yanek, D.M. Becker, L.C. Becker, C. Kooperberg, B. Keating, J. Reis, H. Tang, E. Boerwinkle, Y. Kamatani, K. Matsuda, N. Kamatani, Y. Nakamura, M. Kubo, S. Liu, A. Dehghan, J.F. Felix, A. Hofman, A.G. Uitterlinden, C.M. van Duijn, O.H. Franco, D.L. Longo, A.B. Singleton, B.M. Psaty, M.K. Evans, L.A. Cupples, J.I. Rotter, C.J. O’Donnell, A. Takahashi, J.G. Wilson, S.K. Ganesh, and M.A. Nalls for the CHARGE Hematology, COGENT, and RIKEN Blood Working Groups: Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics, 23:6944-6960, 2014
  25. Q. Cai, B. Zhang, H. Sung, S.-K. Low, S.-S. Kweon, W. Lu, J. Shi, J. Long, W. Wen, J-Y. Choi, D.-Y. Noh, C.-Y. Shen, K. Matsuo, S.-H. Teo., M.K. Kim, U.S. Khoo, M. Iwasaki, M. Hartman, A. Takahashi, K. Ashikawa, K. Matsuda, M.-H. Shin, M.H. Park, Y. Zheng, Y.-B. Xiang, B.-T. Ji, S.K. Park, P.-E. Wu, C.-N. Hsiung, H. Ito, Y. Kasuga, P. Kang, S. Mariapun, S.H. Ahn, H.S. Kang, K.Y.K. Chan, E.P.S. Man, H. Iwata, S. Tsugane, H. Miao, J. Liao, Y. Nakamura, M. Kubo, The DRIVE GAME-ON Consortium, R.J. Delahanty, Y. Zhang, B. Li, C. Li, Y.-T. Gao, X.-O. Shu, D. Kang, W. Zheng: Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1. Nature Genetics, 46 :886-890, 2014
  26. B.M. Wolpin, C. Rizzato, P. Kraft, C. Kooperberg, G.M. Petersen, Z. Wang, A.A. Arslan, L. Beane-Freeman, P.M. Bracci, J. Buring, F. Canzian, E.J. Duell, S. Gallinger, G.G. Giles, G.E. Goodman, P.J. Goodman, E.J. Jacobs, A. Kamineni, A.P. Klein, L.N. Kolonel, M.H. Kulke, D. Li, N. Malats, S.H. Olson, H.A. Risch, H.D. Sesso, K. Visvanathan, E. White, W. Zheng, C.C. Abnet, D. Albanes, G. Andriotti, M.A. Austin, R. Barfield, D. Basso, S.I. Berndt, M.-C. Boutron-Ruault, M. Brotzman, M.W. Büchler, H.B. Bueno-de-Mesquita, P. Bugert, L. Burdette, D. Campa, N.E. Caporaso, G. Capurso, C. Chung, M. Cotterchio, E. Costello, J. Elena, N. Funel, J.M. Gaziano, N. Giese, E.L. Giovannucci, M. Goggins, M.J. Gorman, M. Gross, C.A. Haiman, M. Hassan, K. Helzlsouer, B.E. Henderson, E.A. Holly, N. Hu, D.J. Hunter, F. Innocenti, M. Jenab, R. Kaaks, T.J. Key, K.-T. Khaw, E.A. Klein, M. Kogevinas, J. Kupcinskas, R.C. Kurtz, A. LaCroix, M.T. Landi, S. Landi, L.L. Marchand, A. Mambrini, S. Mannisto, R.L. Milne, Y. Nakamura, A.L. Oberg, K. Owzar, S. Panico, A.V. Patel, P.H.M. Peeters, U. Peters, A. Piepoli, M. Porta, F.X. Real, E. Riboli, N. Rothman, A. Scarpa, X.-O. Shu, D.T. Silverman, P. Soucek, M. Sund, R. Talar-Wojnarowska, P.R. Taylor, G.E. Theodoropoulos, M. Thornquist, A. Tjønneland, G.S. Tobias, D. Trichopoulos, P. Vodicka, J. Wactawski-Wende, N. Wentzensen, C. Wu, H. Yu, K. Yu, A. Zeleniuch-Jacquotte, R. Hoover, P. Hartge, C. Fuchs, S. Chanock, R.S. Stolzenberg-Solomon, L. Amundadottir: Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer Nature Genetics, 46:994-1000, 2014
  27. Z. Deng, K. Matsuda, C. Tanikawa, J. Lin, Y. Furukawa, R. Hamamoto and Y. Nakamura:  Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity. Neoplasia, 16:656-664, 2014
  28. K.L. Yap, K. Kiyotani, K. Tamura, T. Antic, M. Jang, M. Montoya, A. Campanile, P.Y. Yew, C. Ganshert, T. Fujioka, G.D. Steinberg, P.H. O’Donnell, and Y. Nakamura: Whole exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival. Clinical Cancer Research, 20: doi: 10.1158/1078-0432.CCR-14-0257, 2014
  29. H. Fang, R. Yamaguchi, X. Liu, Y. Daigo, P.Y. Yew, C. Tanikawa, K. Matsuda, S. Imoto, S. Miyano, and Y. Nakamura: Quantitative T Cell Repertoire Analysis by Deep cDNA Sequencing of T Cell Receptor  and  Chains using Next-Generation Sequencing (NGS) OncoImmunology, :DOI: 10.4161/21624011.2014.968467, 2014
  30. V. Saloura, H.-S. Cho, K. Kyiotani, H. Alachkar, Z. Zuo, M. Nakakido, T. Tsunoda, T. Seiwert, M. Lingen, J. Licht, Y. Nakamura, and R. Hamamoto: WHSC1 Promotes Oncogenesis through Regulation of NIMA-related-kinase-7 in Squamous Cell Carcinoma of the Head and Neck. Molecular Cancer Research, 12:DOI: 10.1158/1541-7786.MCR-14-0292-T, 2014
  31. K. Matsuda, A. Takahashi, W. Obara, Y. Nasu, K. Inoue, K. Tamura, I. Yamasaki, Y. Naya, C. Tanikawa, R. Cui, M. Namiki, Y. Tomita, H. Nishiyama, K. Kohri, T. Deguchi, M. Nakagawa, M. Yokoyama, T. Miki, H. Kumon, T. Fujioka, M. Kubo, Y. Nakamura, and T. Shuin: Genome wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population Human Molecular Genetics, :doi: 10.1093/hmg/ddu512, 2014
  32. M. Liu, P.E. Goss, J.N. Ingle, M. Kubo, Y. Furukawa, A. Batzler, G.D. Jenkins, E.E. Carlson, Y. Nakamura, D.J. Schaid, J.-A.W. Chapman, L.E. Shepherd, M.J. Ellis, S. Khosla, L. Wang, and R.M. Weinshilboum: Aromatase Inhibitor-Associated Bone Fractures: A Case-Cohort GWAS and Functional Genomics. Molecular Endocrinology, :dx.doi.org/10.1210/me.2014-1147, 2014
  33. Y. Yamaguchi, H. Yamaue, T. Okusaka, K. Okuno, H. Suzuki, T. Fujioka, A. Otsu, Y. Ohashi, R. Shimazawa, K. Nishio, J. Furuse, H. Minami, T. Tsunoda, Y. Hayashi, and Y. Nakamura, The Committee of Guidance for Peptide Vaccines for the Treatment of Cancer, The Japanese Society for Biological Therapy: Guidance for peptide vaccines for the treatment of cancer. Cancer Science, 105:924-931, 2014
  34. A.C. Wu, B.E. Himes, J. Lasky-Su, A. Litonjua, S.P. Peters, J. Lima, M. Kubo, M. Tamari, Y. Nakamura, W. Qiu, S.T. Weiss, K. Tantisira: Inhaled corticosteroid treatment modulates ZNF432 gene variant’s effect on bronchodilator response in asthmatics. Journal of Allergy and Clinical Immunology, 133:723-728, 2014
  35. Y. Matsuo, J.-H. Park, T. Miyamoto, S. Yamamoto, S. Hisada, H. Alachkar, and Y Nakamura: TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis Science Translational Medicine, 259:259ra145, 2014
  36. K. Sone, L. Piao, M. Nakakido, K. Ueda, T. Jenuwein, Y. Nakamura and R. Hamamoto Critical role of lysine 134 methylation on histone H2AX for -H2AX production and DNA repair. Nature Communications, 5:DOI: 10.1038/ncomms6691, 2014
  37. H. Alachkar,  M. Mutonga, K.H. Metzeler, N. Fulton, G. Malnassy, T. Herold, K. Spiekermann, S.K. Bohlander, W. Hiddemann, Y. Matsuo, W. Stock, and Y. Nakamura: Preclinical efficacy of Maternal Embryonic Leucine-zipper Kinase (MELK) Inhibition in Acute Myeloid Leukemia Oncotarget, 512371-12382, 2014
  38. Y. Yoshitake, D. Fukuma, A. Yuno, M. Hirayama, H. Nakayama, T. Tanaka, M. Nagata, Y. Takamune, K. Kawahara, Y. Nakagawa, R. Yoshida, A. Hirosue, H. Ogi, A. Hiraki, H. Jono, A. Hamada, K. Yoshida, Y. Nishimura, Y. Nakamura, and M. Shinohara: Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS. Clinical Cancer Research, DOI: 10.1158/1078-0432. CCR-14-0202, 2014
  39. T. Yamaguchi, T. Yamaguchi, Y. Furukawa, Y. Nakamura, N. Matsubara, H. Ishikawa, M. Arai, N. Tomita, K. Tamura, K. Sugano, C. Ishioka, T. Yoshida, Y. Moriya, H. Ishida, T. Watanabe, and K. Sugihara for HNPCC Registry and Genetic Testing Project of the Japanese Society for Cancer of the Colon and Rectum Comparison of clinical features between suspected familial colorectal cancer type X and Lynch syndrome in Japanese patients with colorectal cancer: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum. JJCO, :doi: 10.1093/jjco/hyu190, 2014

37 Publications cited >500 times (among 1466 publications (August 1, 2017)

B. Vogelstein, E.R. Fearon, S.R. Hamilton, S. Kern, A.C. Presinger, M. Leppert, Y. Nakamura, R. White, L. Smets and J.L. Bos: Genetic alterations during colorectal tumor development.  New Eng. J. Med., 319:525-532, 1988

6958

citations

The International HapMap Consortium: A haplotype map of the human genome. Nature, 437:1299-1320, 2005

4774

The International HapMap Consortium: The International HapMap Project. Nature, 426:789-796, 2003

4097

The International HapMap Consortium: A second generation human haplotype map of over 3.1 million SNPs. Nature, 449:851-861, 2007

3960

K.W. Kinzler, M.C. Nilbert, L. Su, B. Vogelstein, T.M. Bryan, D.B. Levy, K.J. Smith, A.C. Preisinger, P. Hedge, D. McKechnie, R. Finniear, A. Markham, J. Groffen, M.S. Boguski, S.F. Alschul, A. Horii, H. Ando, Y. Miyoshi, Y. Miki, I. Nishisho, Y. Nakamura: Identification of FAP locus genes from chromosome 5q21. Science, 253:661-665, 1991

2409

S.J. Baker, E.R. Fearon, J.M. Nigro, S.R. Hamilton, A.C. Preisinger, J.M. Jessup, P. vanTuinen, D.H. Ledbetter, D.F. Barker, Y. Nakamura, R. White and B. Vogelstein: Chromosome 17 Deletions and p53 mutations in Colorectal Carcinomas. Science, 244:217-221, 1989

2213

Y. Nakamura, M. Leppert, P. O'Connell, Roger Wolff, T. Holm, M. Culver, C. Martin, E. Fujimoto, M. Hoff, E. Kumlin and R. White: Variable number of tandem repeat (VNTR) markers for human gene mapping. Science, 235:1616-1622, 1987

2028

I. Nishisho, Y. Nakamura, Y. Miyoshi, Y. Miki, H. Ando, A. Horii, K. Koyama, J. Utsunomiya, S. Baba, P. Hedge, A. Markham, A.J. Krush, G. Petersen, S.R. Hamilton, M.C. Nilbert, D.B. Levy, T.M. Bryan, A.C. Preisinger, K.J. Smith, L. Su, K.W. Kinzler, and B. Vogelstein: Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science, 253:665-669, 1991

1868

B. Vogelstein, E.R. Fearon, S.E. Kern, S.R. Hamilton, A.C. Preisinger, Y. Nakamura and R. White: Allelotype of colorectal carcinomas. Science, 244:207-211, 1989

1533

K. Oda, H. Arakawa, T. Tanaka, K. Matsuda, C. Tanikawa, T. Mori, H. Nishimori, K. Tamai, T. Tokino, Y. Nakamura, and Y. Taya: p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell, 102:849-862, 2000

1233

The International Warfarin Pharmacogenetics Consortium: Estimation of the warfarin dose with clinical and pharmacogenetic data. New Eng. J. Med., 360:753-764, 2009

1188

P. C. Sabeti, P. Varilly, B. Fry, J. Lohmueller, E. Hostetter, C. Cotsapas, X. Xie, E. H. Byrne, S. A. McCarroll, R. Gaudet, S. F. Schaffner, E. S. Lander, and The International HapMap Consortium: Genome-wide detection and characterization of positive selection in human populations. Nature, 449:913-918, 2007

The International Cancer Genome Consortium: International network of cancer genome projects. Nature, 464:993-998, 2010

1121

 

 

1043

A. Suzuki, R. Yamada, X. Chang, S.Tokuhiro, T. Sawada, M. Suzuki, M. Nagasaki, M. Nakayama-Hamada, R.Kawaida, M. Ono, M. Ohtsuki, H. Furukawa, S. Yoshino, M. Yukioka, S. Touma, T. Matsubara, S. Wakitani, R. Teshima, A. Sekine, A.Iida, A. Takahashi, T. Tsunoda, Y. Nakamura, and K. Yamamoto: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nature Genetics, 34:395-402, 2003

1042

C. Larsson, B. Skogseid, K. Obeg, Y. Nakamura, M. Nordenskjold: Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature, 332:85-87, 1988

1029

S. Satoh, Y. Daigo, Y. Furukawa, T. Katoh, N. Miwa, T. Nishiwaki, T. Kawasoe, H. Ishiguro, M. Fujita, T. Tokino, Y. Sasaki, S. Imaoka, M. Murata, T. Shimano, Y. Yamaoka, and Y. Nakamura: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nature Genetics, 24:245-250, 2000

968

Y. Miyoshi, H. Nagase, H. Ando, A. Horii, S. Ichii, S. Nakatsuru, T. Aoki, Y. Miki, T. Mori and Y. Nakamura: Somatic mutation of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Human Molecular Genetics, 1:229-233, 1992

W. Satake, Y. Nakabayashi, I. Mizuta, Y. Hirota, C. Ito, M. Kubo, T. Kawaguchi, T. Tsunoda, M. Watanabe, A. Takeda, H. Tomiyama, K. Nakashima, K. Hasegawa, F. Obata, T. Yoshikawa, H. Kawakami, S. Sakoda, M. Yamamoto, N. Hattori, M. Murata, Y. Nakamura, and T. Toda: Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nature Genetics, 41:1303-1307, 2009

968

 

 

876

H. Tanaka, H. Arakawa, T. Yamaguchi, K. Shiraishi, S. Fukuda, K. Matsui, Y. Takei, and Y. Nakamura: A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint DNA damage. Nature, 404:42-49, 2000

869

K. Ozaki, Y. Ohnishi, A. Iida, A. Sekine, R. Yamada, T. Tsunoda, H. Sato, H. Sato, M. Hori, Y. Nakamura, and T. Tanaka: Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction. Nature Genetics, 32:650-654, 2002

839

D. Barker, E. Wright, K. Nguyen, L. Cannon, P. Fain, D. Goldger, D. T. Bishop, J. Carey, B. Bety, H. Willard, J. S. Waye, G. Greig, L. Leinward, Y. Nakamura, P. O'Connell, M. Leppert, J.-M. Lalouel, R. White and M. Skolnick: Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17. Science, 236:1100-1102, 1987

762

K.W. Kinzler, M.C. Nilbert, B. Vogelstein, T.M. Bryan, D.B. Levy, K.J. Smith, A.C. Preisinger, S.R. Hamilton, P. Hedge, A. Merkham, M. Carlson, G. Joslyn, J. Groden, R. White, Y. Miki, I. Nishisho and Y. Nakamura: Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science, 251:1366-1370, 1991

762

T. Ota et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nature Genetics, 36:40-45, 2004

754

K. Kobayashi, Y. Nakahori, M. Miyake, Y. Nomura, M. Yoshioka, K. Saito, M. Osawa, J. Goto, Y. Nakagome, I. Kanazawa, Y. Nakamura, K. Tokunaga, and T. Toda: An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy (FCMD). Nature, 394:388-392, 1998

736

M. Leppert, M. Dobbes, P. Scambler, P. O'Connell, Y. Nakamura, D. Stauffer, S. Woodward, R. Burt, J. Hughes, E. Gardner, M. Lathrop, J. Wasumuth, J.-M. Lalouel, R. White: The gene for familial polyposis coli maps to the long arm of chromosome 5. Science, 238:1411-1413, 1987

697

R.A. Gatti, I. Berkel, E. Border, G. Braedt, P. Charmley, P. Concannon, F. Ersoy, T. Foroud, N.J.G. Jaspers, K. Lange, G.M. Lathrop, M. Leppert, Y. Nakamura, M. Paterson, W. Salser, O. Sanal, W. Shan, J. Silver, R.S. Sparkes, E. Susi, D. Weeks, R. White and F. Yoder: Localization of ataxia-telangiectasia gene to chromosome 11q22.3. Nature, 336:577-580, 1988

669

H. Okabe, S. Satoh, T. Kato, O. Kitahara, R. Yanagawa, Y. Yamaoka, T. Tsunoda, Y. Furukawa and Y. Nakamura: Genome-wide analysis of gene expression in human hepatocellular carcinomas using cDNA microarray: identification of genes involved in viral carcinogenesis and tumor progression. Cancer Research, 6:2129-2137, 2001

620

K. Yasuda, K. Miyake, Y. Horikawa, K. Hara, H. Osawa, H. Furuta, Y. Hirota, H. Mori, A. Jonsson, Y. Sato, K. Yamagata, Y. Hinokio, H.-Y. Wang, T. Tanahashi, N. Nakamura, Y. Oka, N. Iwasaki, Y. Iwamoto, Y. Yamada, Y. Seino, H. Maegawa, A. Kashiwagi, J. Takeda, E. Maeda, H. D. Shin, Y. M. Cho, K. S. Park, H. K. Lee, M. C. Y. Ng, R. C. W. Ma, W.-Y. So, J. C. N. Chan, V. Lyssenko, T. Tuomi, P.Nilsson, L. Groop, N. Kamatani, A. Sekine, Y. Nakamura, K. Yamamoto, T. Yoshida, K. Tokunaga, M. Itakura, H. Makino, K. Nanjo, T. Kadowaki, and M. Kasuga: Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nature Genetics, 40:1092-1097, 2008

618

T. Sato, A. Tanigami, K. Yamakawa, F. Akiyama, F. Kasumi, G. Sakamoto and Y. Nakamura: Allelotype of breast cancer: Cumulative allele losses promote tumor progression in primary breast cancer. Cancer Research, 50:7184-7189, 1990 

589

R. Hamamoto, Y. Furukawa, M. Morita, Y. Iimura, F. P. Silva, M. Li, R. Yagyu and Y. Nakamura:  SMYD3 encodes a novel histone methyltransferase involved in the proliferation of cancer cells. Nature Cell Biology, 6:731-740, 2004

588

H. Unoki, A. Takahashi, T. Kawaguchi, K. Hara, M. Horikoshi, G. Andersen, D.P.K. Ng, J. Holmkvist, K. Borch-Johnsen, T. J. Rgensen, A. Sandbaek, T. Lauritzen, T. Hansen, S. Nurbaya, T. Tsunoda, M. Kubo, T. Babazono, H. Hirose, M. Hayashi, Y. Iwamoto, A. Kashiwagi, K. Kaku, R. Kawamori, E. S. Tai, O. Pedersen, N. Kamatani, T. Kadowaki, R. Kikkawa, Y. Nakamura, and S. Maeda: SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nature Genetics, 40:1098-1102, 2008

581

H. Han, A. Yanagisawa, Y. Kato, J. Park, and Y. Nakamura: Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Research, 53:5087-5089, 1993

577

T. Mizuguchi, G. Collod-Beroud, T. Akiyama, M. Abifadel, N. Harada, T. Morisaki, D. Allard, M. Varret, M. Claustres, H. Morisaki, M. Ihara, A. Kinoshita, K. Yoshiura, C. Junien, T. Kajii, G. Jondeau, T. Ohta, T. Kishino, Y. Furukawa, Y. Nakamura, N. Niikawa, C. Boileau, and N. Matsumoto: Heterozygous TGFBR2 mutations in Marfan syndrome. Nature Genetics, 36:855-860, 2004

562

Y. Miyoshi, H. Ando, H. Nagase, I. Nishisho, A. Horii, Y. Miki, T. Mori, J. Utsunomiya, S. Baba, G. Petersen, S.R. Hamilton, K.W. Kinzler, B. Vogelstein, Y. Nakamura: Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc. Natl. Acad. Sci. USA, 89:4452-4456, 1992

558

S. Tokuhiro, R. Yamada, X. Chang, A. Suzuki, Y. Kochi, T. Sawada, M. Suzuki, M. Nagasaki, M. Ohtsuki, M. Ono, H. Furukawa, M. Nagashima, S. Yoshino, A. Mabuchi, A. Sekine, S. Saito, A. Takahashi, T. Tsunoda, Y. Nakamura and K. Yamamoto: An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nature Genetics, 35:341-348, 2003

556

A. Tenesa, S.M. Farrington, J.G.D. Prendergast, M.E. Porteous, M. Walker, N. Haq, R.A. Barnetson, E. Theodoratou, R. Cetnarskyj, N. Cartwright, R. Wilson, C. Semple, A.J. Clarke, F.J.L. Reid, L.A. Smith, K. Kavoussanakis, T. Kossler, P.D.P. Pharoah, S. Buch, C. Schafmayer, J. Tepel, S. Schreiber, H. Volzke, C.O. Schmidt, J. Hampe, S. Wilkening, F. Canzian, J. Chang-Claude, M. Hoffmeister, H. Brenner, G. Capella, V. Moreno, I.J. Deary, J.M. Starr, I.P.M. Tomlinson, E. Webb, R.S. Houlston, G. Rennert, D. Ballinger, L. Rozek, S.B. Gruber, K. Matsuda, T. Kidokoro, Y. Nakamura, B.W. Zanke, C.M.T. Greenwood, J. Rangrej, R. Kustra, A. Montpetit, T.J. Hudson, S. Gallinger, H. Campbell, and M.G. Dunlop:   A genome-wide association scan identifies colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics, 40:631-637, 2008

Y. Miyoshi, K. Iwao, Y. Nagasawa, T. Aihara, Y. Sasaki, S. Imaoka, M. Murata, T. Shimano, and Y. Nakamura: Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Research, 58:2524-2527, 1998

528

 

 

 

 

 

509